DePaul Art Museum is a center for modern and contemporary art that features Chicago-based artists in dialogue with artists from around the globe. In 2020, DePaul Art Museum launched a multiyear Latinx Initiative, aimed at increasing the visibility of Latinx artists in its exhibitions and programs. LatinXAmerican is a major group exhibition that explores the shifting, and at times contradictory, social, cultural, political and artistic identities of Latinx and Latin American artists of different generations. The exhibition is accompanied by panel discussions, a podcast series, and collaborations with the Lit y Luz Festival, which fosters Chicago-Mexico City artistic exchange.

Stockyard Institute: 25 Years of Art and Radical Pedagogy brings together archival material, objects, installations and a radio station from the Stockyard Institute, an ongoing civic and artistic practice founded in 1995 by artist Jim Duignan in the Back of the Yards community of south Chicago.

Forthcoming is Creative Resistance/Everyday Violence: 20 Years After Guantanamo an exhibition that marks the twentieth anniversary of the establishment of Guantanamo detention site by looking at the ways artists address the moral and legal implication of detention without charge.